Chapter 2

C O L L A B O R A T I V E  T R E A T M E N T  O F  T R A U M A T I Z E D
C H I L D R E N  A N D  T E E N S

S A X E G N , E L L I S H B , K A P L O W J ,
G U I L F O R D P R E S S ( 2 0 0 6 )


Survival Circuits
How traumatic stress is about survival-in-the-moment
LEARNING OBJECTIVES
To understand how traumatic stress responses relate to systems of the brain developed for survival.
To understand how traumatic stress responses relate to ‘survival-in-the-moment’.
To review neurodevelopmental variables related to traumatic stress responses.
To review the critical relationship between the social environment and the developing brain.
Icons Used in this Chapter
Essential Point
Academic Point
Quotation
Case Discussion
Traumatic stress is about survival-in-the-moment. Survival-in-the-moment is controlled by ancient systems of the brain and body that we call the Survival Circuits. The Survival Circuits control the way we process traumatic events and the hold that these events may have on us throughout our lives. We begin our discussion of the foundations of Trauma Systems Therapy (TST) with a review of these Survival Circuits and their implications for treating traumatic stress. First, let us briefly think about the survival. Any discussion of survival must begin with the amazing work of the nineteenth century T
Charles Darwin (1809-1882)
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British naturalist named Charles Darwin (1809-1882). As most of us know, Darwin proposed his theory of evolution to explain the natural origins of human beings. Through his observations of animals on the Galapagos Islands, he noted that the animals who were best equipped to survive were the most likely to live long enough to pass on their survival enhancing traits to their offspring. Traits that helped promote survival become maintained and those that did not promote survival died out. This is a process called adaptation. New traits can suddenly develop in a given organism out of what is called “chance mutation”. Those new traits that give their owner enough of an advantage to reproduce become integrated into the biology of the species. Over many millions of years, this process creates species with ever increasing advantages for survival.
Although Darwin’s revolutionary proposal, The Origin of Species (859), was published almost 150 years ago; it anticipated and is supported by groundbreaking work in genetics, molecular biology, and developmental neuroscience, published only in the last ten years. The need to survive has sculpted our biology. This sculpture has occurred over many millions of years and has given us, in our genes, our cells, our brains, and our bodies, powerful mechanisms to survive. Survival is at the core of traumatic stress. It is enacted on the moment we perceive that our life is in danger; and the surival circuits control it. 1
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Survival is at the core of traumatic stress. It is enacted on the moment we perceive that our life is in danger; and the survival circuits control it.
Survival Circuits
We human beings are at the top of the evolutionary ladder. What puts us up there? We have a biology that has been refined over millions of years giving us amazing systems
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necessary to master our environments. We have biology’s with the potential to create great works of art, science, mathematics, technology, and culture. Our ability to master our environments, and to achieve the enormous advances in diverse areas of pursuit, requires our evolutionarily advanced neurobiological systems to be working properly. The main part of our biology that has allowed us such powerful and flexible adaptive capacities is our brain, particularly the higher order systems of our brains located in what is called the cerebral cortex.
Lower order systems of the brain, such as those that control basic emotionality, physiology, and survival-motivated behavior are found in the brains of lower animal species and are also powerfully embedded deep within our human brains. These lower neurobiological systems are largely responsible for maintaining our survival so that our higher order brain systems can do their great work. One of the primary ways that these advanced, higher order brain systems become unable to do their great work is if there is a perceived threat to survival in the environment. When this occurs, by virtue of millions of years of evolution and adaptation, all neurobiological systems work at only one goal: to foster survival-in-the-moment. As described, the survival circuits are responsible for survival-in-the-moment responses. It is the engagement of these survival circuits, in situations where life is not actually in danger that causes the problem of traumatic stress.
One of the primary ways that these advanced, higher order brain systems become unable to do their great work is if there is a perceived threat to survival in the environment.
It is therefore extremely important to understand how seemingly innocuous stimuli can create the extreme survival-motivated responses, in order to help traumatized children respond in more adaptive ways.
Once these powerful and ancient systems are triggered the brain and the body enter a state of processing in order to maintain survival against life threatening events. The problem is, for individuals with traumatic stress, most of the time there is no current and immediate life threat. The individual’s brain and body are responding to a past life threat in the present. Almost all problems in those with traumatic stress relate to these powerful survival circuits. It is therefore extremely important to understand how seemingly innocuous stimuli can create the extreme survival-motivated responses, in order to help traumatized children respond in more adaptive ways.
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The importance of these survival circuits will be integrated into the definition of traumatic stress in the next version of the Diagnostic and Statistical Manual of Mental Disorders (DSM V) (First, 2006), the important guidebook that defines all mental disorders in the United States and in most areas of the world (APA, 1994). The proposed name for the group of disorders that includes fear, anxiety and Posttraumatic Stress Disorder will be called Stress-induced and Fear Circuitry Disorders. These disorders can be understood through the descriptions of the survival circuits detailed in this chapter.
Survival-in-the-Moment
As we will describe, there is a great focus within TST to understand specific moments in the child’s life. In essence, these moments are when the survival circuits get engaged. These are the moments when children feel and do things that become very problematic for themselves and/or others and lead to the need for mental health intervention. If these moments were somehow, magically, removed from a child’s life there would be no need for mental health intervention. Traumatic stress, as described, is about survival-in-the-moment. TST is about replacing these survival-in-the-moment responses with responses that allow a child to grow and thrive.
TST is about preventing survival-in-the-moment responses.
The Survival Circuits connote a way in which the brain processes stimuli that are potentially life threatening, and translates this perception into life sustaining responses. In traumatic stress, there are fundamental problems with this type of processing and responses become highly maladaptive. In order to understand this more fully, it is important to know what goes on within the brain and body, between the potentially life threatening stimulus and the potentially life preserving response. We begin the discussion of this fundamental process with a description of a moment-in-the-life of a child with traumatic stress. Consider what happens to Denise, in-the-moment:
It is important to know what goes on within the brain and body, between the potentially life threatening stimulus and the potentially life preserving response.
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Denise is a 16 year-old girl with a history of sexual abuse from her mother’s boyfriend. While at a local mall with friends she saw a man who frightened her. She later reported that this man reminded her of her mother’s boyfriend. Denise remembers becoming extremely anxious and became flooded with memories of sexual abuse. She does not remember walking away. Her friends found her curled up in a bathroom stall, unresponsive.
This is the case of an adolescent with a history of sexual abuse who was functioning well, until she saw a man who reminded her of the man who abused her. When she saw this man, her brain rapidly shifted to survival-in-the-moment. It is exactly this moment that must be understood and treated within TST.
Denise generally functions well. Most of the time, her higher order brain systems are engaged and doing their great work. Denise was at the mall having fun with friends. She was happy, socializing, and very calm. At the moment she saw this man, she entered a state of extreme fear and then dissociation. These states of extreme fear and dissociation are entirely motivated by survival. Traumatized children go from the stimulus (a traumatic reminder) to response (an extreme emotional state) without the ability to think, calm, and sooth. This response can be immediate, extreme, and outside of conscious control. An essential part of intervention is to help children to calm themselves when confronted by a traumatic reminder so that they do not enter these extreme survival-in-the-moment states. Denise goes immediately from the stimulus to this extreme state. If treatment could help her to think, before she responded, she might have the potential to calm and sooth herself so the extreme responses would not occur.
One of the main goals of intervention is to prevent children from going from stimulus to immediate extreme response. A critical problem for traumatized children is that they frequently live in environments riddled with traumatic reminders. The stresses of ongoing family violence, community violence,
The transition between states of calmness and states of terror when confronted by a traumatic reminder is the hallmark of traumatic stress.
How do children with such problems managing emotions and behavior when faced with a threat, navigate a world full of threats?
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parental substance abuse and mental illness, for example, are frequently part of the everyday life of a traumatized child. How do children with such problems managing emotions and behavior when faced with a threat, navigate a world full of threats? All children must learn to identify, manage, and reasonably respond to signals from his or her social environment. How does a child with traumatic stress learn to do this, when she hears any loud voice as angry, or misinterprets a classmate’s playful nudge as aggressive? How much more difficult is this task when the child is exposed to ongoing domestic or community violence, endures parental mental illness and substance abuse, or fears impending homelessness? This is the problem that our intervention model is designed to address.
If Denise does not immediately respond with extreme emotional or behavioral changes and can think about the stimuli of a man who reminded her of her mother’s boyfriend, she could perhaps understand that the man IS NOT her mother’s boyfriend and that more adaptive responses are possible. Once Denise has the ability to think in this way, a lot of good things can happen for her. The ability to think in this way requires the engagement of the higher order brain systems that we described. Again: These higher order systems are undermined by the lower order systems in situations of survival-in-the-moment. How can higher order brain systems STAY engaged in situations of threat, TST is designed to help traumatized children’s brains do this.
How can higher orderbrain systems STAYengaged in situations ofthreat, TST is designedto help traumatizedchildren’s brains do this.
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TST starts with the understanding that traumatized children frequently live in environments saturated with traumatic reminders (the stimulus) and have limited ability to regulate their emotional and behavioral responses. As figure 1 illustrates, they go from stimulus to extreme immediate responses (survival-in-the-moment states). Two types of interventions are instituted as illustrated in figure 2, a) Social Environmental interventions and b) Self-Regulatory interventions. Social environmental intervention is about surveying the social environment for sources of traumatic reminders and trying to diminish these reminders (the stimulus). Self-Regulatory interventions are about using both psychotherapeutic and psychopharmacological means to enhance the child’s capacity to control the immediate responding to the stimulus. As illustrated in the figure 3, when the stimuli are diminished and the child has increasing capacity to regulate responses, the potential is developed for thinking about alternative responses. For reasons that are clear in the illustration, we call this a “wedge” of cognition.
Social-Environmental Self-Regulatory
Social-Environmental Self-Regulatory
Fig 2. Two types of interventions
Intervention
Fig 3. The wedge of cognition
Intervention
Fig 1. From Stimulus to immediate, extreme response
Stimulus
Response
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Your moment in the zoo
In order to best understand how this works, we will take a walk through your brain in a given moment between a stressful stimulus and a response. Please imagine yourself in the following situation:
You are walking down a path in your own thoughts. It is a nice, sunny day. You feel calm. Suddenly you notice an object coming to you from the right. You freeze. Your feet are planted in the ground. Your heart is pounding. You are sweating…You then recognize that the object walking towards you is a lion…that it is in a cage…and that you are in the zoo… You continue walking and continue to enjoy your pleasant day at the zoo.
The moment described in the above scenario probably would take under 2 seconds. Within that time, there was a lot of activity that occurred in your brain that illustrate very important ideas about the emotional nervous system and its integral role in survival. These ideas are very important to understand when we consider the nature of traumatic stress. The moment, illustrated in figure 4, and the following discussion is adapted from the work of Joseph LeDoux, a neuroscientist at Rockefeller University who has conducted some of the pioneering work on emotional processing in the brain, particularly related to fear. His books The Emotional Brain (1998) and The Synaptic Self (2002) are very important for understanding how the brain processes threatening stimuli and for understanding survival-in-the-moment. We also rely on Antonio Damasio’s The Feeling of What Happens (1999) in our discussion of how emotion, memory, and consciousness fit together. In this brief chapter, it is hard to truly do justice to these great areas of research, and parts of the discussion oversimplify. Nevertheless, there are important components of emotional processing in the brain that help to understand the nature of traumatic stress and its intervention.
According to LeDoux, there are two emotional processing systems of the brain. These two systems work closely together such that we are usually unaware that there are these discrete systems. These systems are critical for our survival and, more-or-less, detail the
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aforementioned distinction between the higher order and lower order systems of the brain. LeDoux calls these two systems the “Low road” and “High road” of emotional processing. We call these systems considered together, the Survival Circuits.
Figure 4 illustrates these two roads of emotional processing. As can be seen, the stimulus of the lion in the zoo passes through the sensory thalamus along two separate paths. One path (the Low Road) goes directly to a structure called the amygdala that prepares the body for emergency responses. This pathway is marked by very quick transmission of sensory information to give the organism basic information about danger. This pathway is unconscious and does not contain contextual information. It sacrifices the details in the service of speed so that you can respond before you are eaten! The other path (the high road) travels to cortical areas (the sensory cortex, the prefrontal cortex, and the medial temporal lobe memory system) that process the danger signal, assess its degree of threat, and transmit signals to the amygdala regarding whether the stimulus signals safety or danger. This type of processing can powerfully determine the most adaptive response in-the-moment.
Figure 5: The Survival Circuits
Transmission of Danger Information
Transmission of Danger OR Safety Information
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The information processing shared by the sensory cortex, the medial temporal lobe memory system, and the prefrontal cortex is very important for determining an accurate perception of the stimulus and for determining an adaptive response to this perception of the stimulus. The red arrows in figure 4 indicate transmission of signals indicating danger. The red/green arrows indicate transmission of signals that may indicate either danger or safety. Safety information (green) traveling from high road brain systems (the sensory cortex, the prefrontal cortex, and the medial temporal lobe memory system) to the amygdala, diminish amygdala responding and serve to regulate emotion. When danger information (red) is transmitted from these high road systems, it maintains the Low road, survival-in-the-moment, response. This type of information could have been transmitted if, for example, the lion you encountered had actually escaped from its cage. The amygdala also communicates directly back to high road systems. These upward pathways indicated by the red arrows are very important for understanding the nature of traumatic memory. The remainder of this chapter details the relevance of these concepts for traumatic stress.
Stimulus, Sensation, Context, Consciousness, and Response
As we walk you through your brain between the stimulus of the lion in the zoo and your emotional and behavioral responses, we will walk through five constructs related to brain processing that are captured by LeDoux’s High road and Low road of emotional processing. These five constructs, considered together, explain many areas of experience, symptoms, and functioning of individuals with traumatic stress. It is important to note that these five constructs are not necessarily engaged sequentially but may be involved in parallel at various times in the processing of the stimuli.
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1) The Stimulus
People’s response to the external world is based on how they appraise external stimuli. Most stimuli that are processed do not signal a threat to life and limb. Some stimuli, however, indicate such a threat. The way in which people make this distinction is critical for survival and for adaptive responding. At the zoo, you were confronted with a stimulus. How did you eventually decide it was safe? How much did you need to think about the lion walking toward you before you knew that you were (very) unlikely to be attacked? What about Denise in the mall? How did she decide that the stimulus of a man walking toward her indicated that her life could be threatened? How did that appraisal determine a response? As will be detailed next, much of this appraisal is done unconsciously such that we are completely unaware of the information that bears on survival-laden responses in the moment. It is very fortunate that these responses can be processed outside of conscious awareness. Conscious processing takes time. By the time needed to think about whether the Lion walking toward you was a threat, you might be eaten (if, for example, the lion had escaped from its cage)!
At the zoo, you wereconfronted with astimulus. How did youeventually decide it wassafe? How much did youneed to think about thelion walking toward youbefore you knew that youwere (very) unlikely to beattacked?
2) Sensory Processing
All the stimuli that confront us are processed through a structure called the sensory thalamus. This structure has components for processing stimuli from the 5 senses. The stimulus that you and Denise processed was visual. Once the visual stimulus of the lion in the zoo, and the man in the mall, engages the sensory thalamus, it is transmitted in two possible directions. One direction is to the sensory cortex for higher order processing including conscious perception of the stimulus. LeDoux calls this direction the “High Road”. The other possible direction is straight to the lateral nucleus of the Amygdala (the “Low Road”). We will review Amygdala processing in more detail when we discuss Emotional and Behavioral Response Systems a little later. What is important to note is this “Low Road” is extremely fast and unconscious. Low road processing transmits bits of threat-related information very quickly to the Amygdala whose job is then to initiate emergency responses. This type of information does not include the
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contextual details. It sacrifices these details in the service of speed so that you can respond to maximize your chance of survival given the threat. The High Road, which includes the sensory cortex, the Medial Temporal Lobe memory system (especially a structure called the hippocampus), and the prefrontal cortex are all engaged to help get the details of the situation so that the most adaptive response is possible given the stimuli. It is these systems, working together that help an individual know just how threatening the stimuli are. In order to do this sensory cortex must engage long term memory stores that contain experience with similar stimuli, the medial temporal memory system must place the stimulus in the proper context of time and place, and the prefrontal cortex must put this information into an individual’s direct awareness (working memory) in order for considered action to occur. The Low Road, Amygdala system responds rapidly to incomplete bits of information and facilitates memory storage in such an incomplete way. This is probably why people have flashbacks when they are reminded of a traumatic event. Flashbacks are, in essence, bits or flashes of emotionally laden memory. This type of memory storage is unconscious and is called the Implicit Emotional Memory System. This memory system is critical for survival because it stores the memory of survival threatening stimuli so that when such stimuli are re-encountered survival laden responding can be very quick. Because this storage is so incomplete, it leads to misperception of threatening stimuli on future occasions. This helps explain why Denise immediately had a survival-in-the-moment response when she saw the man at the mall.
3) Contextual Processing
As described, the Low Road, Amygdala system does its work in a contextless way. It is ONLY concerned with survival. The Medial Temporal Lobe Memory System, particularly the hippocampus, provides the contextual details. This is the system that works with the sensory cortex and other areas of the higher order cerebral cortex to bring accurate context-laden details provided by the long term memory systems of the cerebral cortex to help an individual
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accurately understand the understand proper time and place of the stimulus.
The ability to accurately place a given stimulus in proper time and place is extremely important. What made you know that the stimulus of the lion was not life threatening? You could correctly place it in the zoo and connect it with your long-term memory stores of your experiences in zoos. To the degree that none of these memories includes being attacked by a lion in a zoo, but rather pleasant times in the zoo and the safety of lions in zoos, you will feel safe and continue to have your current pleasant day at the zoo. In fact, your initial response (heart pounding, sweating, feet planted, etc) was mediated by the Amygdala Low Road but terminated so quickly and unconsciously that you could have continued completely unaware that it occurred. What terminated this immediate, low road response? The high road medial temporal memory system, indicating you were safe by allowing you access to information so that you could correctly recognize the context you were in. This information would include that you have been to the zoo many times before, that you have never been attacked by a lion, that you have never before seen anyone attacked by a lion, and that lions in zoos, generally, do not leave their cages. Access to this information, diminishes the bodies emergency responses and leads to the sense of calmness that you felt only moments after you were alarmed. In figure 4, the arrow (when green) shows this regulation of response from the Medial Temporal Lobe Memory System to the Amygdala.
The Low Road, Amygdalasystem does its work in acontextless way. It isONLY concerned withsurvival.
4) Consciousness
Consciousness implies awareness. It is the awareness, in-the-moment, of the stimulus, the response, and/or the emotional state of the body. It is also, in-the-moment, the awareness that there is an agent (YOU) that perceives the stimulus, carries out the response, and/or feels the emotional state of the body. As Antonio Damasio says, consciousness is the bringing together of the self and the object (stimulus), in-the-moment. Accordingly consciousness has a lot to do with our basic sense
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of identity, or the feeling and thought of who we are. As we have described, there is a great deal of processing of stimuli and executing responses that occur completely outside of our awareness. Consciousness is when this processing reaches our awareness or as Demasio says when we ‘step into the light’. Consciousness is strongly influenced by areas of the brain called the prefrontal cortex as shown in figure 4. This is related to what is called ‘working memory’ or the capacity to keep information in awareness, in-the-moment.
Consciousness involvesthe ability to shiftattention to the thingswe want to attend to.When we perceive stimulisuggesting that our life isin danger, however, it isvery hard to attend toanything else.
Consciousness is very important for traumatic stress. When you were walking in the zoo you were initially lost in your thoughts and momentarily not really conscious about being in the zoo. You of course, at any moment could have easily shifted your attention from your thoughts to what you were doing (walking in the zoo) but it is a good thing that you did not need to be completely conscious of the zoo if you did not need to be. If we do not always need to be conscious of the context we are in, than we can then shift our attention to other things and let our higher order brain systems do their great work (perhaps while you were walking in the zoo you were composing a symphony, solving a scientific problem, or trying to solve an interpersonal conflict). Conscious thought is experimental action. It allows us to carefully consider our responses before responding. This is the wedge of cognition described in figure 3. Consciousness involves the ability to shift attention to the things we want to attend to. When we perceive stimuli suggesting that our life is in danger, however, it is very hard to attend to anything else. How might this work for you and for Denise?
You were ‘in your thoughts’ on your walk in the zoo. At some point, the context of the zoo intruded on your consciousness in the form of a lion walking towards you. Prior to achieving this consciousness, your Low road system briefly engaged. Momentarily after your low road system engaged your high road system processed the sensation of the lion, compared it with previous memories of lions in zoos, accurately brought your current context (the zoo) to your moment, and brought some of that information into your consciousness. Each of the high road systems of Sensory cortex (accurate perception), medial temporal lobe memory system (context), and prefrontal cortex (consciousness) sent safe signals (green arrows from Figure 4) to the amygdala, allowing you
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to enjoy your day. Once Denise was stimulated, she was, sadly, far less able to shift her attention back to her good time at the mall. The stimulus of the man who reminded her of her stepfather signaled danger, her low road amygdala system responded rapidly and extremely. Her higher road systems were not able to accurately perceive the stimulus to tell her that the man is not her stepfather and to keep her in the safer context of the mall. Accordingly, what entered her consciousness was only the context of past abuse. Consciousness involves orientation to time, place, and person. In the moment, she was disoriented to when this was, where she was, and who she was. She was a little girl, in her bedroom, being abused.
Another way of describing why your trip to the zoo was calm and peaceful and Denise’s trip to the mall terrifying is that, as LeDoux puts it, the amygdala leads a “hostile takeover of consciousness by emotion (p. 226)”. “..the amygdala leads a hostile takeover of consciousness by emotion (LeDoux, 2002, p. 226)”.
In other words, when presented with a stressful stimulus the emotional nervous system becomes so overwhelmed that what enters an individual’s awareness is dominated by amygdala processing (i.e. fast, fragmented, decontextualized, aroused), rather than high road processing (i.e. slow(er), calm, linear, contextual, and (more) conscious). When Denise saw the man at the mall, the amygdala succeeded in its hostile takeover. When you saw the Lion your higher order systems fought it back (the amygdala… not the lion).
When Denise saw theman at the mall, theamygdala succeeded in itshostile takeover. Whenyou saw the Lion yourhigher order systemsfought it back (theamygdala… not the lion).
5) Emotional and Behavioral Response Systems
The Amygdala, via its Low Road pathway, is designed to quickly and powerfully prepare the body to react and to survive. Accordingly, it
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engages the emotional and behavioral response systems of the body. These systems are very important for survival as they mobilize the body to respond very quickly during situations of danger; so quickly that one is not even aware or conscious of responding. As can be seen in Figure 4, the lateral nucleus of the amygdala, integrates information from both the sensory thalamus (the low road) and the sensory cortex, medial temporal lobe memory system, and prefrontal cortex (the high road) and uses this information to guide powerful, evolutionarily-driven, bodily responses.
Pathways from the amygdala’s lateral nucleus go to its central nucleus to engage systems of the body that will react. This includes hormonal systems via the Hypothalamic-Pituitary-Adrenal (HPA) Axis that releases energy stores using the hormone cortisol; the Locus Coreuleus,/Norepinepherine System that activates the heart and focuses attention on the threat, and the polyvagal system which increases social engagement from the myelinated vagus nerve or immobilization or freezing from the unmyelinated vagus nerve (Porges, 1996). These systems also feed back to the amygdala and to the higher order cortical systems and result in our awareness of the feeling state of our body. An emotion is the awareness of a feeling state of the body (Damasio, 1999). This process of self-awareness is extremely adaptive. It allows an individual to use emotions as signals for effective action and underlies the critical process of emotional regulation that will be detailed in the next chapter. We use this understanding about consciousness of one’s own emotional state to build skills in this area in chapter 12.
This process of self-awareness is extremelyadaptive. It allows anindividual to use emotionsas signals for effectiveaction and underlies thecritical process ofemotional regulation.
The emotional response systems mediated by the central nucleus of the amygdala have strong connections to motivational/behavioral/reward systems mediated by the basal nucleus of the amygdala. The basal nucleus then initiates a pathway that leads to behavioral responses (fighting, running, yelling, etc.) to manage the threatening stimulus. This pathway begins with a structure called the nucleus accumbens and directs bodily nerves and muscles to manage the threat. It is also important that the amygdala’s central nucleus emotional response system is also connected to this behavior/motivation/reward system. This latter pathway leads to the
Survival-related emotioncan clearly cause survival-related behavior. Inchildren with traumaticstress, this survival-related behavior can beviolence, self-mutilation,and suicide. This behaviorusually follows extremeemotional states such aspanic, rage, dissociation,and depression.
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release of dopamine in the nucleus accumbens which facilitates its response to signals from the basal amygdala (LeDoux, 2002). One important practical implication of this connection is that survival-related emotion can clearly cause survival-related behavior. In children with traumatic stress, this survival-related behavior can be violence, self-mutilation, and suicide. This behavior usually follows extreme emotional states such as panic, rage, dissociation, and depression. As will be detailed in chapter 7, our assessment approach operationalizes these basic neurobiological processes.
What about Denise? Denise, as described, does not have a high road system that will help her correctly identify the stimulus and bring the context of the mall to the moment. Her responses are thus entirely mediated by the very quick pathway from the sensory thalamus to the lateral nucleus of the amygdala. Behavioral/Motivational systems activated while in this emotional state include running to the bathroom and freezing (as she lay on the bathroom floor). As described, for Denise this emotional state represented survival-in-the-moment.
The March of the Moments
Traumatic stress in the past, present, and future
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We began this chapter with a discussion of how traumatic stress responses can be understood via survival-in-the-moment. Our detailing of Denise’ response in the mall and your response in the zoo allowed us to describe the neurobiology of these moments through what can be called survival circuits. This way of thinking about traumatic stress is really built on top of how people are put together through the very long process of evolution. This also brings us to an interesting and important idea about human emotion, consciousness, memory, and sense-of-self; and has important implications for treatment: Everything-is-in-the-moment!
Everything-is-in-the-moment!
As described, consciousness involves the capacity (through working memory) to keep only a small set of things in awareness in any given moment. Human consciousness is ONLY a construct for the present. Human consciousness, and therefore, the organization of human experience are moment-by-moment. Memory is the laying down of these present, conscious moments in the brain so that they can be accessible if we need them.
What happens to themoment that has justpast? What makes usknow that these momentsjoined together make upourselves as entities thattravel through time witha continuity of memoryand identity?
What happens to the moment that has just past? What makes us know that these moments joined together make up ourselves as entities that travel through time with a continuity of memory and identity? Our ability to know these critical things requires a process of these moments being laid down, with proper contextual information and relative continuity of emotional experience between moments. In other words, the development of a clear and coherent sense-of-self requires that the high road systems lay down these moments in memory rather than the low road systems. As described, if the pathway from the amygdala to the higher order systems is very active, than the memory that gets laid down is fragmented, disoriented, and decontextualized. Individuals construct a sense of themselves through the stringing together of moments. This is what has been called autobiographical memory. The ability to consciously access memory in a given moment is greatly facilitated if the memory was laid down in a clear, linear, and context-related way. The emotional state a person is in, in-the-moment, facilitates this access. If an individual is in an anxious
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state, for example, it is much easier to access anxiety related memories than calmness memories. When an individual is in a survival-in-the-moment phase, it is very hard to access memories of calm moments. One of the main functions of psychotherapy is to help an individual have access to these memories, in-the-moment.
Present
Moment
Past
Memory
Anticipated
Future
This person occasionally has another, non-extreme, feeling state indicated by the change in color (say, sadness). There is no problem or pathology associated with this feeling state, as it is largely laid down through the higher order systems. The present moment of sadness is experienced with relative calmness, and linear, contextual processing.
To the degree that there is continuity between feeling states in-the-moment, past memory is laid down with relative coherence and is joined with an awareness of the self that is relatively stable over time. In fact, for individuals whose life moments are, more-or-less, laid down in such calm, contextual, and linear ways, their self experience looks more like figure 6. Even though consciousness works moment-by-moment, the brain has a way of blending moments so that self experience is continuous.
Present
Moment
Figure 5
Consider the string of boxes in figure 5. Each box indicates a separate moment in time. Each moment in time is marked by a feeling state indicated by a respective color. Most people have moments and feelings states that look like figure 5. Moments consist of relatively stable, calm feeling states (blue boxes).
Figure 6
Past
Memory
Anticipated
Future
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This fundamental neurological capacity to blend moments is critical for our ability to form a coherent sense of ourselves over time. This capacity is not unlike the way the brain is able to take frame-by-frame images of a movie and construct a complete and continuous story. Consciousness is the movie-of-our-lives. As Damasio says:
“…the neurobiology of consciousness faces two problems: the problem of how the movie-in-the-brain is generated, and the problem of how the brain also generates the sense that there is an owner and observer for that movie.”
Damasio, 1999, pg. 11.
What happens if there is a moment in which survival appears to be threatened?
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Past
Memory
Anticipated
Future
A moment in which survival is perceived as threatened is indicated in figure 7, where blue boxes indicate moments of relative calmness and the red box indicates a survival-in-the-moment state. This experience, like Denise’ moment in the mall is experienced in a highly fragmented, disoriented way. It then gets laid down in memory in such a way so that when some of the contextual signals recur on future occasions, there is a higher likelihood of this survival-in-the-moment state recurring. This is why Denise will have such states of survival related emotion whenever she experiences stimuli of a man reminiscent of her stepfather. This is also why Denise will have such difficulty blending moments as illustrated in figure 6. Denise’ internal world actually looks more like figure 7. Her experience is riddled with episodes of survival-in-the-moment.
As we described, in states of survival-in-the-moment, individuals like Denise can become disoriented to time, place, and person. Denise in these moments feels like a little girl out of control and about to be raped. This is very different from how she feels in her ‘blue’ moments when she feels calm, happy, and like a competent girl who is in control of her life. In a way Denise’ emotional life looks more like figure 9.
Figure 7
Figure 8
Figure 9
Present
Moment
Denise lives parallel lives. Her sense-of-self cannot transition between emotional state, and she grows up with a very fragmented sense of herself. This type of problem occurs in conditions of psychopathology such as the dissociative disorders and some of the personality disorders. The essence of these types of problems have at various times been called Disorders of Extreme Stress, Complex PTSD, and Developmental Trauma Disorder where an individuals sense of self can become state dependant instead of being state independent. Given the obvious corollary difficulties of forming stable relationships when ones own sense-of-self is unstable, and the emotional fluctuations that are part of this instability, children with traumatic stress often grow up with patterns of painful, unstable relationships. Chapter 3, on emotional regulation, describes
Given the obvious corollary difficulties of forming stable relationships when ones own sense-of-self is unstable, and the emotional fluctuations that are part of this instability, children with traumatic stress often grow up with patterns of painful, unstable relationships.
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some details of this process, including its implications for psychiatric diagnosis of traumatized individuals. Chapter 5, on interpersonal relationships details how this pattern of unstable emotion and sense-of-self can lead to significant difficulties with relationships. As we will describe, perhaps the child with traumatic stresses only hope of recovery is the development of stable relationships. It is therefore extremely important that these patterns of survival-in-the moment are addressed in treatment.
Marching into the Future
One of the most devastating effects of traumatic stress is about its effect on children’s ability to think into the future. If consciousness is about the present, and memory is about the past, then planning and anticipation are about the future. This is about the use of present consciousness, and long term memory stores, to anticipate the risk and reward of future events and to plan so that ones needs are met into the future.
One of the most devastating effects of traumatic stress is about its affect on children’s ability to think into the future.
This ability to see into the future is one of the most powerful functions of the human brain. At a basic level, this ability maximizes survival through the ability to calculate survival-related risk given the ever changing environmental variables that are encountered in everyday life. At the zoo, for example, you unconsciously performed a calculation that the lion walking towards you was not likely to pose a risk to your survival because there were a series of metal bars mediating your relationship with the lion. This calculation also extended into the future. You (unconsciously) calculated that for the time you would stay in the zoo, you would be safe. This calculation helped preserve your sense of calm safety at the zoo but was also made with incomplete information. You had no information, for example, about whether the lion’s cage was locked or unlocked. You bet your life that it was locked. Our ability to continually calculate risk is fundamental for our ability to productively navigate our world. This calculation of risk always
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involves incomplete information (your ignorance of whether the cage was actually locked). We must be able to do this well or we will live lives completely restricted by survival-related concerns. Our ability to calculate the likely reward inherent to specific events in the future is critical for our sense of happiness and pleasure; and to the degree that it motivates behavior to increase the likely reward of future events, it motivates creativity.
The parts of the brain that perform these calculations are located in the area called the parietal cortex. The parietal cortex (most specifically the posterior parietal cortex) performs calculations of the likely risk and reward involved in future events. We need to be able to do this effectively. This calculation of ‘high-risk’ of the future event influences the behavioral/motivational/reward circuits to avoid this event. This calculation of low-risk influences the behavioral/motivational/reward circuits to engage with this event if there is a sufficient calculation of the probability of reward related to the event. The posterior parietal cortex calculates probabilities of risk/reward. The results of these calculations strongly influence emotion and behavior. Neuroscientists have become very interested in understanding these types of calculations as a way to understand how the brain influences motivated behavior. This area of neuroscience has been called ‘Neuroeconomics’ (Glimcher, 2003).
In children with traumatic stress these calculations are extremely important. An overestimate of the likely risk in events leads to the serious problem of avoidance of people, places, and things that might remind the child of the trauma. Traumatized children can, therefore, lead overly restrictive lives. It is also clinically important that traumatized children can underestimate the risk of danger and to put themselves in highly dangerous situations. This can happen when the child is not able to act on interpersonal warning signs and therefore forms relationships with individuals who repeat the trauma. Traumatized children also have trouble calculating the likely reward inherent in future events. They underestimate the pleasure that they might experience in relationships and activities. The parietal lobes’ calculations of the probability of risk and reward of future events are a part of an individual’s ability to visualize
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Traumatized children will not be able to see their futures if they are fighting for their lives in the present and if they have trouble seeing any likelihood of rewards or pleasure in future events.
themselves into the future. One of the tragic problems of traumatic stress is this lack of ability to see oneself into the future or as Lenore Terr (1990) has described this sense of a ‘foreshortened future’. Traumatized children will not be able to see their futures if they are fighting for their lives in the present and if they have trouble seeing any likelihood of rewards or pleasure in future events.
A Picture of the Brain
In order to see how closely many of the areas of the Survival Circuits work together, it is important to see how close they are to each other in the brain. This is illustrated in figure 11 from the journal ‘CNS Forum’ where the areas of the brain known to be related to traumatic stress are shown.
As can be seen, the low road, amygdala is situated right beside the high road hippocampus, a critical part of the medial temporal memory system. Both of these areas are in close proximity to the sensory thalamus which passes sensory information to the low road and high road systems, respectively. The emotional and behavioral response systems are also closely related anatomically. The hypothalamus is the lead of the HPA axis, which regulates the stress hormones, required for fight-or-flight. Similarly, the locus coeruleus leads the norepinepherine systems response, which causes heightened attention to the threatening stimulus and increases heart rate to help the body respond to the threat. The prefrontal cortex, as described is critical for holding information in consciousness.
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Although, this chapter is not focused on a full research review of the psychobiology of traumatic stress, it is important to know that many of these systems are affected and even damaged by trauma. Many MRI studies have reported that the amygdala is active during memory of the trauma (e.g. Rauch et. al, 1996; Rauch et. al, 2000; Shin et. al, 2004), other studies have reported a smaller hippocampal size and diminished hippocampal function in those with traumatic stress (e.g. Bremner et al, 1995, Stein et. al, 1997) although this finding has not been replicated in children (Carrion et. al, 2001, DeBellis et. al, 1999) Although a smaller hippocampal size was not found, these investigators did report a smaller volume of the cerebral cortex in general (Carrion et. al, 2001, DeBellis et. al, 1999). There is a large literature on the dysfunction of the HPA axis (e.g. Yehuda et. al, 1990; Yehuda et. al, 1993) and the locus coruleus/norepinepherine system in those with PTSD (e.g. Kosten et. al, 1987; Southwick, et. al, 2003). Newer research has focused on the relationship between the ‘high road’ and ‘low road’ as described in this chapter. Shin and colleagues (2004) found that during a memory of a traumatic event the prefrontal cortex was less active in those with traumatic stress compared to traumatized individuals without traumatic stress. This lower activity of parts of the prefrontal cortex was related to higher activity of the amygdala. Importantly this lower level of prefrontal activity was also related to the degree of traumatic stress symptoms. In other words, this important functional MRI study reported that the high road has difficulty regulating the low road in those with traumatic stress.
Beyond Survival
TST is about understanding how the child’s developing nervous system and its social ecology interact.
TST is about understanding how the child’s developing nervous system and the social environment interact. This is reflected in our description of the Trauma System. In chapter 1, we defined this trauma system as:
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1) A traumatized child who has difficulty regulating emotional states,
2) A social environment and/or system of care that is not sufficiently able to help contain this dysregulation
The social ecology (Bronfenbrenner, 1972) of traumatic stress places the child and his or her developing brain in the center of nested levels of a social environment. The parts of the brain described by the Survival Circuits are at the center of the trauma system. One of the most important implications of the discussion in this chapter on Survival Circuits is how closely linked these circuits are to social environmental stimuli. Some of the details of the trauma system will be fleshed out in the next few chapters. Chapter 3 will detail how the critical developmental construct called emotional regulation works for the traumatized child. As will be seen, ideas of emotional regulation are highly related to the Survival circuits described in this chapter. Chapter 4 details the importance of the social environment and system-of-care for child development and how, exactly, these systems can go wrong for traumatized children. Chapter 5 details the importance of interpersonal relationships for helping or hindering the healthy development of traumatized children. As will be described these interpersonal relationships are considered to be the cusp of the trauma system and strongly mediate the relationship between emotional regulation and the social environment/system-of-care.
The quality of earliest interpersonal relationships sculpts the brains’ Survival circuits to make the child more or less able to regulate emotion when faced with a stress. These ‘working models’ of relationships described in the attachment literature help or hinder the regulation of emotion in future relationships. We will call strong attachment relationships “Signals of Care” because they work, exactly, to counteract survival-in-the-moment when a child is confronted with signals of danger. As will be described, if children live in social environments and systems-of-care that contain sufficient “Signals of
The quality of earliest interpersonal relationships sculpts the brains’ Survival circuits to make the child more or less able to regulate emotion when faced with a stress.
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Care” this will go a long way to minimizing the risk of a survival-in-the-moment response. Trauma Systems Therapy has a strong focus on building these signals of care in the lives of traumatized children.
Finally we end this chapter with some evidence that the Survival Circuits can be changed through the right type of experiences. Peter Kirsh and colleagues (2005) at the National Institute of Mental Health recently reported that the amygdala, the lead of the low road system, can be regulated by a chemical called Oxytocin. Oxytocin is critical in human life for a lot of reasons. It strongly influences a woman’s labor and delivery of her baby. It also strongly mediates breast-feeding and is a chemical know to be critical in animal and human research for bonding and healthy attachment. Oxytocin is naturally released during social bonding from the earliest phases of development and is one of the critical mediators of social attachments. The release of Oxytocin during safe social contact causes a sense of calmness. Figure 12 shows the results of the Kirsh experiment.
Individuals were shown pictures of frightening faces and of frightening scenes. In the placebo condition the areas of the brain that were most active, indicated by the red color, was the amygdala on both sides of the brain. When these same individuals were given a dose of Oxytocin and shown the exact same frightening pictures, the amygdala was no longer active.
Figure 12
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The profound implications of this experiment go way beyond the possible therapeutic value of giving frightened people injections of Oxytocin. We all release Oxytocin naturally in the context of safe and caring relationships and the release of this chemical leads to our feelings of calm contentment, in these safe and caring relationships. If the lead of the Survival Circuit is the Low Road Amygdala, and the Amygdala is regulated by Oxytocin; than strong, safe, caring relationships will help to regulate the Amygdala and therefore the Survival Circuit.
The silver lining in this cloud of trauma is that just as bad events can change the brain in deleterious ways, good events can change the brain in beneficial ways.
The silver lining in the cloud of trauma is that just as bad events can change the brain in deleterious ways, good events can change the brain in beneficial ways. We designed TST to help get the brain, and the child who owns it, to have experiences that will help them have the future they deserve.
REFERENCES THAT NEED TO BE ADDED
Yehuda R, Southwick SM, Nussbaum G, et al: Low urinary cortisol excretion in patients with posttraumatic stress disorder. J Nerv Ment Disease 1990; 178: 366-369
Yehuda R, Southwick SM, Krystal JH, et al: Enhanced suppression of cortisol following a low dose of dexamethasone in combat veterans with posttraumatic stress disorder. Am J Psychiatry 1993; 150: 83-96
Kosten TR, Mason JW, Giller EL, et al: Sustained urinary norepinepherine and epinepherine elevation in PTSD. Psychoneuroendocrinology 1987; 12: 13-20
Southwick SM, Krystal JH, Morgan A, et al: Abnormal noradrenergic function in posttraumatic stress disorder. Arch Gen Psychiatry 1993; 50: 266-274
Bremner JD, Randall P, Scott TM, Bronen RA, Seibyl JP, Southwick SM, Delaney RC, McCarthy G, Charney DS, Innis RB: MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am J Psychiatry 1995; 152:973–981
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Bremner JD, Randall P, Vermetten E, Staib L, Bronen RA, Mazure C, Capelli S, McCarthy G, Innis RB, Charney DS: Magnetic resonance imaging-based measurements of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report. Biol Psychiatry 1997; 41:23–32
Gurvits TV, Shenton ME, Hokama H, Ohta H, Lasko NB, Gilbertson MW, Orr SP, Kikinis R, Jolesz FA, McCarley RW, Pitman RK: Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder. Biol Psychiatry 1996; 40:1091–1099
Gilbertson MW, Shenton ME, Ciszewski A, Kasai K, Lasko NB, Orr SP, Pitman RK: Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci 2002, 5:1242–1247
First M (2006), Stress-Induced and Fear Circuitry Disorders Proceedings of Future of Psychiatric Diagnosis: Refining the Research Agenda, NIMH, Bethesda
Kirsch P et al. (2005) Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci 25:11489-93
Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, Lasko NB, Peters PM, Metzger LJ, Dougherty DD, Cannistraro PA, Alpert NM, Fischman AJ, Pitman RK. (2004) Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. Arch Gen Psychiatry. Feb;61(2):168-76.
Rauch SL, Whalen PJ, Shin LM, McInerney SC, Macklin ML, Lasko NB, Orr SP, Pitman RK (2000).Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study.Biol Psychiatry. 2000 May 1;47(9):769-76
Terr L, Too Scared to Cry: Psychic trauma in Chilodhood. Basic Books, NY, 1990

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